Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12225968 | 0.80 | TSHR (0.52) | ALDH1A1TDP1TSHRLMNAHTT | |
| SCHEMBL7924131 | 0.72 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TDP1TSHRLMNA | |
| SCHEMBL7935215 | 0.72 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1TDP1TSHRLMNA | |
| SCHEMBL7936398 | 0.70 | LMNA (0.53) | ALDH1A1L3MBTL1TDP1TSHRLMNA | |
| SCHEMBL2533708 | 0.70 | MAPT (0.64) | ALDH1A1TDP1TSHRLMNAHTT | |
| SCHEMBL2530971 | 0.70 | KMT2A (0.58) | ALDH1A1L3MBTL1TDP1TSHRLMNA | |
| SCHEMBL12225960 | 0.70 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1TDP1TSHRLMNA | |
| SCHEMBL30191958 | 0.69 | RAB9A (0.53) | ALDH1A1TSHRLMNAUSP2KDM4E | |
| SCHEMBL1493487 | 0.69 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1TDP1LMNAHTT | |
| SCHEMBL13319445 | 0.66 | DAO (0.57) | ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034003-A2 | BENZYLTHIOTETRAZOLE INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-03-25 | — | — | WO | disclosed |