Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928973 | 0.85 | CYP1A2 (0.38) | BRD4CREBBPACHEPDE7APDE7B | |
| SCHEMBL30422252 | 0.72 | BRD4 (0.39) | BRD4CREBBP | |
| SCHEMBL13360866 | 0.72 | BRD4 (0.39) | BRD4CREBBP | |
| SCHEMBL2480306 | 0.72 | ACHE (0.41) | BRD4ACHE | |
| SCHEMBL4650091 | 0.69 | HTR2C (0.38) | — | |
| SCHEMBL13198514 | 0.68 | PDE7A (0.39) | PDE7APDE7B | |
| SCHEMBL29428654 | 0.68 | PDE7A (0.39) | PDE7APDE7B | |
| SCHEMBL22368668 | 0.67 | ALDH1A1 (0.33) | BRD4PDE7A | |
| SCHEMBL5951495 | 0.67 | ACHE (0.52) | BRD4CREBBPACHEMAOAMAOB | |
| SCHEMBL12205326 | 0.67 | ACHE (0.36) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028213-A2 | N-SULFONAMIDO POLYCYCLIC PYRAZOLYL COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 2010-03-11 | — | — | WO | disclosed |