SCHEMBL7936557

SCHEMBL7936557

CC(C)=C1OC(=O)N(c2cc(Oc3ncccn3)c(Cl)cc2F)C1=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
PPOX P50336 8/20 0.35
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7936534 0.85 P2RY1 (0.36) ALDH1A1
SCHEMBL7926374 0.84 ALDH1A1 (0.43) ALDH1A1
SCHEMBL9577486 0.83 PPOX (0.51) ALDH1A1PPOX
SCHEMBL9577463 0.80 PPOX (0.47) ALDH1A1PPOXHPGD
SCHEMBL9577505 0.80 PPOX (0.42) ALDH1A1PPOXHPGD
SCHEMBL9620060 0.79 CUL4A (0.43) ALDH1A1PPOX
SCHEMBL9577438 0.79 PPOX (0.50) PPOX
SCHEMBL9577496 0.79 PPOX (0.38) PPOX
SCHEMBL7932830 0.77 PPOX (0.32) PPOXHPGD
Pentoxazone SCHEMBL38904 0.77 PPOX (0.51) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303543-B1 Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-10-16 US disclosed
US-6121201-A HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-09-19 US disclosed