Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | STAT5B | P51692 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952689 | 1.00 | HTR2C (0.42) | HTR2CSLC6A4GLSKMT2ACTSL | |
| SCHEMBL3108959 | 0.89 | NR1H4 (0.45) | HTR2CSLC6A4GLSKMT2ACTSL | |
| SCHEMBL30964962 | 0.87 | GLS (0.40) | HTR2CSLC6A4GLSKMT2ACTSL | |
| SCHEMBL297071 | 0.85 | ALDH1A1 (0.51) | HTR2CSLC6A4GLSKMT2ACTSL | |
| SCHEMBL14969145 | 0.85 | HTR2C (0.43) | HTR2CSLC6A4GLSKMT2ARIPK1 | |
| SCHEMBL3109559 | 0.85 | HTR2C (0.41) | HTR2CSLC6A4GLSKMT2ACTSL | |
| SCHEMBL3110201 | 0.83 | GLS (0.43) | HTR2CSLC6A4GLSKMT2ACTSL | |
| SCHEMBL3116212 | 0.83 | LTA4H (0.42) | HTR2CSLC6A4GLSCTSLCTSB | |
| SCHEMBL3109868 | 0.83 | GLS (0.42) | HTR2CSLC6A4GLSCTSLCTSB | |
| SCHEMBL24289750 | 0.82 | HTR2C (0.40) | HTR2CSLC6A4GLSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |