Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.67 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120337 | 0.91 | GABRA1 (0.71) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL29829095 | 0.89 | AKR1B1 (0.72) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL8791 | 0.89 | AKR1B1 (0.72) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL14764373 | 0.87 | AKR1B1 (0.57) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL19900571 | 0.85 | HMGB1 (0.68) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL71912 | 0.85 | AKR1B1 (0.59) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL2730028 | 0.85 | AKR1B1 (0.55) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL29430565 | 0.85 | PTGS2 (0.56) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL5106925 | 0.85 | PTGS2 (0.56) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL6035567 | 0.85 | AKR1B1 (0.55) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281320-B1 | POLYOLEFIN CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-08-28 | — | — | US | claimed |
| US-6281320-B1 | POLYOLEFIN CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-08-28 | — | — | US | disclosed |