Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.72 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | IAPP | P10997 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791 | 1.00 | AKR1B1 (0.72) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| Ethylenediamine SCHEMBL6041178 | 0.92 | AKR1B1 (0.62) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL7937087 | 0.89 | AKR1B1 (0.67) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL28717700 | 0.84 | IAPP (0.56) | AKR1B1IAPPTDP1ALDH1A1RECQL | |
| SCHEMBL72309 | 0.84 | AKR1B1 (1.00) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL30449014 | 0.84 | AKR1B1 (1.00) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL6054330 | 0.83 | IAPP (0.50) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL30940438 | 0.82 | AKR1B1 (0.58) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL4284420 | 0.82 | AKR1B1 (0.95) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| Ammonia Solution, Strong SCHEMBL10886656 | 0.82 | AKR1B1 (0.95) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274989-A9 | Compositions and Methods of Using the Same for Treatment of Neurodegenerative and Mitochondrial Disease | MITOKININ, INC. (US) | 2022-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274989-A9 | Compositions and Methods of Using the Same for Treatment of Neurodegenerative and Mitochondrial Disease | NLN, NME4, COQ8A | AKR1B1 2371/4885DUSP3 3561/4885PTPN5 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.