Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088720 | 0.88 | TDP1 (0.48) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL1220306 | 0.88 | ALDH1A1 (0.48) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL20353182 | 0.88 | ALDH1A1 (0.48) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL21799857 | 0.88 | ALDH1A1 (0.48) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL18660140 | 0.88 | MAPT (0.50) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL17852303 | 0.88 | L3MBTL1 (0.48) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL2495982 | 0.87 | TDP1 (0.54) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL17710412 | 0.85 | TDP1 (0.52) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL809501 | 0.84 | ALDH1A1 (0.61) | TDP1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL11528155 | 0.84 | PKM (0.57) | TDP1ALDH1A1CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903331-B1 | Process for inhibiting polymerization during distillation of vinyl aromatics | UOP INC (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0903331-A1 | Process for inhibiting polymerization during distillation of vinyl aromatics | UOP (US) | 1999-03-24 | — | — | EP | disclosed |
| US-5869717-A | ADDING A NITROSO COMPOUND SUCH AS N-NITROSO-N,N'-DI-3-PENTYL-P-PHENYLENEDIAMINE. | UOP LLC (US) | 1999-02-09 | — | — | US | disclosed |