Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732963 | 0.85 | ALDH1A1 (0.51) | MAPTNPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL19732922 | 0.83 | LMNA (0.45) | TP53RAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL19732918 | 0.82 | LMNA (0.59) | LMNAALDH1A1KCNA5PLAU | |
| SCHEMBL19732934 | 0.81 | LMNA (0.48) | L3MBTL1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL19732946 | 0.80 | LMNA (0.51) | RAB9ALMNAALDH1A1F2NPSR1 | |
| SCHEMBL19732948 | 0.80 | HTT (0.55) | L3MBTL1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL19732930 | 0.80 | POLB (0.48) | MAPTTP53SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL21926455 | 0.77 | MAPT (0.48) | L3MBTL1MAPTTP53NPC1SMN1; SMN2 | |
| SCHEMBL19732921 | 0.77 | MEN1 (0.44) | L3MBTL1MAPTTP53SMN1; SMN2TSHR | |
| SCHEMBL19752616 | 0.75 | L3MBTL1 (0.44) | L3MBTL1TP53NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |