Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928854 | 0.92 | MAOB (0.47) | ABCG2MAOBNPC1SMN1; SMN2CASP3 | |
| SCHEMBL7937699 | 0.86 | ABCG2 (0.49) | ABCG2NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL7935034 | 0.84 | PLAU (0.40) | ABCG2MAOBNPC1SMN1; SMN2CASP3 | |
| SCHEMBL7937733 | 0.83 | MAPT (0.43) | ABCG2NPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL6050235 | 0.82 | MIF (0.46) | NPC1RAB9ACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7928856 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTGAACYP1A1CYP1A2 | |
| SCHEMBL6050365 | 0.82 | CYP1A2 (0.43) | ABCG2MAPTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7937836 | 0.81 | APP (0.48) | MAOBNPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL8500385 | 0.78 | TDP1 (0.47) | MAPTCYP1A1CYP1A2CYP1B1BRD4 | |
| SCHEMBL7940260 | 0.78 | TLR9 (0.42) | MAOBMAPTGAAAPPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835868-B1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | LILLY CO ELI (US) | 2001-08-29 | — | — | EP | disclosed |
| US-5929090-A | NOVEL COMPOUNDS FOR TREATING ESTROGEN DEPRIVATION CAUSED BY MENOPAUSE OR OVARIECTOMY; TREATING OSTEOPOROSIS, CARDIOVASCULAR DISEASES, AND ENDOMETRIOSIS | ELI LILLY AND COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0835868-A1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |