Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937758 | 0.88 | ALDH1A1 (0.61) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL7947627 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3265135 | 0.83 | ALDH1A1 (0.67) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3946896 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3946586 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL4308534 | 0.75 | ADRA1D (0.43) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4318665 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL3950369 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL4038215 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E | |
| SCHEMBL4357338 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |