Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 12/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | CASP1 | P29466 | 7/20 | 0.35 |
| ▸ | CASP7 | P55210 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 4/20 | 0.33 |
| ▸ | MTOR | P42345 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937858 | 0.80 | CYP1A2 (0.49) | CYP1A2CYP3A4ALOX15ALDH1A1CASP1 | |
| SCHEMBL7945084 | 0.72 | CYP1A2 (0.47) | CYP1A2CYP3A4ALDH1A1CASP1CASP7 | |
| SCHEMBL3227728 | 0.69 | SCN8A (0.37) | CYP1A2CYP3A4ALDH1A1CASP1CASP7 | |
| SCHEMBL7937867 | 0.66 | ALDH1A1 (0.36) | CYP1A2CYP3A4ALDH1A1CASP1CASP7 | |
| SCHEMBL7946218 | 0.66 | CYP1A2 (0.60) | CYP1A2CYP3A4ALOX15ALDH1A1CASP1 | |
| SCHEMBL7944564 | 0.65 | CYP1A2 (0.54) | CYP1A2CYP3A4ALOX15ALDH1A1CASP1 | |
| SCHEMBL7945987 | 0.65 | TYRO3 (0.36) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL7938231 | 0.64 | CYP1A2 (0.60) | CYP1A2CYP3A4ALOX15ALDH1A1CASP1 | |
| SCHEMBL7947006 | 0.64 | ALDH1A1 (0.34) | CYP1A2CYP3A4ALDH1A1CASP1CASP7 | |
| SCHEMBL7938346 | 0.63 | ALDH1A1 (0.38) | CYP1A2ALDH1A1CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |