Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 4/20 | 0.36 |
| ▸ | MERTK | Q12866 | 4/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 4/20 | 0.35 |
| ▸ | CASP7 | P55210 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947006 | 0.86 | ALDH1A1 (0.34) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7944716 | 0.85 | CYP1A2 (0.39) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7944000 | 0.84 | ALDH1A1 (0.33) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7944790 | 0.84 | ADORA2A (0.37) | ALDH1A1CYP1A2HSD17B10CYP2D6LMNA | |
| SCHEMBL7938052 | 0.81 | CCND1 (0.38) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7938054 | 0.81 | AKT1 (0.41) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7938346 | 0.81 | ALDH1A1 (0.38) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7937747 | 0.79 | HSF1 (0.35) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7943995 | 0.76 | HSF1 (0.36) | HPGDALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL3227759 | 0.75 | ALDH1A1 (0.39) | HPGDALDH1A1CYP1A2CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |