SCHEMBL793813

SCHEMBL793813

COc1cc(C=O)ccc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.68
TSHR P16473 1/20 0.68
HPGD P15428 4/20 0.61
TDP1 Q9NUW8 2/20 0.61
TRIM24 O15164 1/20 0.61
ALDH5A1 P51649 1/20 0.61
ABAT P80404 1/20 0.61
TRIM33 Q9UPN9 1/20 0.61
FDPS P14324 1/20 0.58
LMNA P02545 2/20 0.57
AOX1 Q06278 1/20 0.56
MAPT P10636 5/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
TTR P02766 1/20 0.53
ALDH1A3 P47895 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL3864454 0.88 ALDH1A1 (0.54) ALDH1A1TSHRHPGDTDP1TRIM24
SCHEMBL335717 0.84 ALDH1A1 (0.68) ALDH1A1TSHRHPGDTDP1TRIM24
SCHEMBL29952908 0.84 ALDH1A1 (0.68) ALDH1A1TSHRHPGDTDP1TRIM24
3,4-Dimethoxybenzaldehyde SCHEMBL29364994 0.81 ALDH1A1 (1.00) ALDH1A1TSHRHPGDTDP1TRIM24
3,4-Dimethoxybenzaldehyde SCHEMBL25202 0.81 ALDH1A1 (1.00) ALDH1A1TSHRHPGDTDP1TRIM24
3,4-Dimethoxybenzaldehyde SCHEMBL5308959 0.81 ALDH1A1 (1.00) ALDH1A1TSHRHPGDTDP1TRIM24
3,4-Dimethoxybenzaldehyde SCHEMBL1330962 0.81 ALDH1A1 (1.00) ALDH1A1TSHRHPGDTDP1TRIM24
SCHEMBL31471656 0.80 LMNA (0.54) ALDH1A1TSHRHPGDTDP1TRIM24
SCHEMBL16952090 0.80 TUBB4A (0.46) ALDH1A1TSHRHPGDTDP1TRIM24
SCHEMBL16954405 0.80 TRPA1 (0.61) ALDH1A1TSHRHPGDTDP1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661596-A Preparation method and application of 1, 2-dioxan luminous compound 苏州亚科科技股份有限公司 2025-03-21 CN claimed
CN-119569553-A Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2025-03-07 CN claimed
CN-117050112-A DOPO derivative containing benzazepine as well as preparation method and application thereof 西华大学 2023-11-14 CN claimed
CN-119569553-B Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2026-04-21 CN disclosed
CN-119569553-B Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2026-04-21 CN disclosed
EP-4232431-B1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LHOTSE BIO INC (US) 2025-08-13 EP disclosed
CN-119661596-A Preparation method and application of 1, 2-dioxan luminous compound 苏州亚科科技股份有限公司 2025-03-21 CN disclosed
CN-119569553-A Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2025-03-07 CN disclosed
CN-119569553-A Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2025-03-07 CN disclosed
CN-119569553-A Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2025-03-07 CN disclosed
CN-111848598-B Heterocyclic compound, application thereof and composition containing same 健艾仕生物医药有限公司 2024-12-10 CN disclosed
EP-0180818-A2 Benzoyl ureas and intermediates BAYER AG (DE) 1986-05-14 EP disclosed
EP-0172509-A2 Process for the preparation of optically active, substituted 1,4-dihydropyridines and their use as medicaments CASSELLA Aktiengesellschaft (DE) 1986-02-26 EP disclosed
US-4558058-A HYPOTENSIVE AGENTS CASSELLA AKTIENGESELLSCHAFT (DE) 1985-12-10 US disclosed
EP-0116708-A1 Substituted 1,4-dihydropyridines, method for their preparation and their use as pharmaceuticals CASSELLA Aktiengesellschaft (DE) 1984-08-29 EP disclosed
US-4239908-A N-aralkenyl-N'-cyano-N\"-(heterocyclylthioalkyl)-guanidines G.D. SEARLE & CO. (US) 1980-12-16 US disclosed
US-4182774-A Method of inhibiting blood platelet aggregation with 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof A. H. ROBINS COMPANY, INCORPORATED (US) 1980-01-08 US disclosed
US-4126635-A ANTICHOLESTEROL, BLOOD PLATELET AGGREGATION INHIBITION A. H. ROBINS COMPANY, INCORPORATED (US) 1978-11-21 US disclosed
US-4045576-A ANTI-INFLAMMATORY METHODS USING 2-AMINO-3-(5- AND 6-)BENZOYLPHENYLACETIC ACIDS, ESTERS AND METAL SALTS THEREOF AND THE COMPOUNDS A. H. ROBINS COMPANY, INCORPORATED (US) 1977-08-30 US disclosed
US-4024274-A Benzylamine derivatives and process for preparing them HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed