Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604992 | 1.00 | DNM1 (0.68) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL8645293 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL895681 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL11643413 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL9117820 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL23248613 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL6684700 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL17743602 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL9117833 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL10609910 | 0.93 | DNM1 (0.71) | DNM1ALDH1A1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963589-A4 | ELECTROSTATIC DISSIPATIVE COMPOSITION | TECHMER PM (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0963589-A1 | ELECTROSTATIC DISSIPATIVE COMPOSITION | Techmer PM (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5863466-A | POLYURETHANE, POLYESTER WITH QUATERNARY AMMONIUM COMPOUND MIXTURE FOR REDUCTION OF CHARGE IN PLASTICS TO REDUCE ACCIDENTS FROM FIRE OR EXPLOSION | TECHMER PM | 1999-01-26 | — | — | US | disclosed |
| WO-1998035359-A9 | ELECTROSTATIC DISSIPATIVE COMPOSITION | — | 1999-01-14 | — | — | WO | disclosed |
| WO-1998035359-A1 | ELECTROSTATIC DISSIPATIVE COMPOSITION | TECHMER PM (US) | 1998-08-13 | — | — | WO | disclosed |