Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15923866 | 0.85 | CFTR (0.36) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3907144 | 0.81 | CFTR (0.38) | SMN1; SMN2ALDH1A1POLBEPHX1MEN1 | |
| SCHEMBL6721810 | 0.81 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1POLBEPHX1MEN1 | |
| SCHEMBL7935563 | 0.79 | CFTR (0.37) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27494342 | 0.79 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1POLBEPHX1MEN1 | |
| SCHEMBL27393143 | 0.79 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL50032 | 0.79 | KDM4E (0.50) | SMN1; SMN2ALDH1A1POLBEPHX1MEN1 | |
| SCHEMBL23042497 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL18628618 | 0.75 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL20045680 | 0.75 | CA2 (0.36) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218498-B1 | USEFUL IN PREPARING MOISTURE CURABLE RTV-1 COMPOSITIONS, AND ARE USEFUL IN DIVERSE PROCESSES WHERE SCAVENGING OF PROTIC MATERIALS, PARTICULARLY WATER, IS DESIRED. | WACKER-CHEMIE GMBH (DE) | 2001-04-17 | — | — | US | disclosed |