SCHEMBL15923866

SCHEMBL15923866

NNC(=O)NCCC(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.36
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HDAC3 O15379 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7938534 0.85 SMN1; SMN2 (0.39) CFTRALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL3141758 0.77 KDM4E (0.39) ALDH1A1KMT2A
SCHEMBL902364 0.76 SMN1; SMN2 (0.43) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL7935563 0.76 CFTR (0.37) CFTRALDH1A1POLBSMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL1695238 0.74 SMN1; SMN2 (0.42) ALDH1A1POLBSMN1; SMN2DGAT1
SCHEMBL6721810 0.73 ALDH1A1 (0.37) CFTRALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL3907144 0.73 CFTR (0.38) CFTRALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL20045680 0.73 CA2 (0.36) CFTRALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL19593402 0.72 EPHX1 (0.50) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL50032 0.71 KDM4E (0.50) CFTRALDH1A1POLBSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2934142-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO Dow AgroSciences LLC (US) 2015-10-28 EP disclosed
WO-2014120355-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-08-07 WO disclosed