SCHEMBL7938649

SCHEMBL7938649

CC1=Cc2ccccc2C1[Hf](Cl)(Cl)(C1C(C)=Cc2ccccc21)=[Ge](C)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933055 0.86 LMNA (0.33) LMNA
SCHEMBL7933187 0.84 LMNA (0.32) LMNA
SCHEMBL7936107 0.81 GABRP (0.30)
SCHEMBL7939078 0.77 ALDH1A1 (0.32)
SCHEMBL12475632 0.74 LMNA (0.31) LMNA
SCHEMBL218412 0.74 LMNA (0.31) LMNA
SCHEMBL218503 0.72 LMNA (0.33) LMNA
SCHEMBL4477667 0.71 ALDH1A1 (0.34) LMNA
SCHEMBL218520 0.71
SCHEMBL4275893 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed