SCHEMBL7939078

SCHEMBL7939078

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Hf](Cl)(Cl)(C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21)=[Ge](C)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7926735 0.89 ALDH1A1 (0.32) ALDH1A1MAPTPKMHPGDHSD17B10
SCHEMBL7933102 0.88 KDM4E (0.32) ALDH1A1
SCHEMBL7936107 0.85 GABRP (0.30)
SCHEMBL8604969 0.79 KDM4E (0.33)
SCHEMBL818878 0.78 KDM4E (0.34) ALDH1A1MAPT
SCHEMBL5853881 0.78 KDM4E (0.32) ALDH1A1
SCHEMBL7212494 0.78 HTR1A (0.32) ALDH1A1
SCHEMBL6914199 0.78 ALDH1A1 (0.32) ALDH1A1MAPTPKMHPGDHSD17B10
SCHEMBL7933047 0.78
SCHEMBL7938649 0.77 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed