Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7936183 | 0.70 | HTR6 (0.31) | — | |
| SCHEMBL7036593 | 0.66 | — | — | |
| Biphenyl SCHEMBL27831108 | 0.55 | ALDH1A1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL8162678 | 0.55 | — | — | |
| Hydrochloric Acid SCHEMBL31374398 | 0.54 | — | — | |
| SCHEMBL7629651 | 0.53 | HPRT1 (0.45) | — | |
| SCHEMBL28750445 | 0.53 | HPRT1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL819246 | 0.52 | HTR2A (0.39) | — | |
| Chlorobenzene SCHEMBL11842612 | 0.52 | TSHR (0.58) | — | |
| Ethylene SCHEMBL2879207 | 0.50 | HTR2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |