Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913309 | 0.87 | LMNA (0.47) | KMT2ADRD2DRD4DRD3ROCK2 | |
| SCHEMBL6815320 | 0.83 | ROCK2 (0.49) | DRD2DRD4DRD3ROCK2LMNA | |
| SCHEMBL6816499 | 0.75 | ALDH1A1 (0.53) | KMT2AALDH1A1LMNAPOLBMAPT | |
| SCHEMBL4218472 | 0.74 | DCUN1D1 (0.62) | KMT2ADRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL6814550 | 0.74 | LMNA (0.61) | KMT2ADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL6814767 | 0.74 | SCN8A (0.48) | LMNADCUN1D1OPRM1OPRD1ACHE | |
| SCHEMBL7640628 | 0.72 | MAPT (0.48) | KMT2AALDH1A1LMNAPOLBMAPT | |
| SCHEMBL23805141 | 0.70 | KMT2A (0.66) | KMT2ADRD2DRD4DRD3ROCK2 | |
| SCHEMBL27837802 | 0.70 | LTA4H (0.56) | KMT2ADRD2DRD4DRD3ROCK2 | |
| SCHEMBL6819624 | 0.70 | NAPRT (0.61) | KMT2AALDH1A1POLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |