Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939791 | 0.86 | MAPT (0.63) | DRD4MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8038873 | 0.82 | MEN1 (0.59) | DRD4MAPK1MEN1KMT2ADRD2 | |
| SCHEMBL7939813 | 0.82 | HTR1A (0.58) | DRD4HTR7DRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL8038700 | 0.82 | MEN1 (0.58) | DRD4MAPK1MEN1KMT2ADRD2 | |
| SCHEMBL7933353 | 0.81 | DRD4 (0.50) | DRD4MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7939838 | 0.80 | DRD2 (0.60) | DRD4MAPTMEN1KMT2ADRD2 | |
| SCHEMBL7942668 | 0.79 | SLC6A2 (0.51) | DRD4MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9225440 | 0.75 | MAPK1 (0.81) | DRD4ALDH1A1MAPK1ADRA1DADRA1A | |
| SCHEMBL7939817 | 0.75 | MAPK1 (0.56) | DRD4MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7940912 | 0.72 | MAPT (0.47) | DRD4MAPTALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | claimed |
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |