Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8038700 | 0.99 | MEN1 (0.58) | MEN1KMT2ADRD2GRM2DRD4 | |
| SCHEMBL8049534 | 0.84 | MEN1 (0.58) | MEN1KMT2ADRD2GRM2DRD4 | |
| SCHEMBL7939196 | 0.82 | DRD4 (0.53) | MEN1KMT2ADRD2DRD4MAPK1 | |
| Fumaric Acid SCHEMBL8051623 | 0.78 | MEN1 (0.51) | MEN1KMT2ADRD2GRM2DRD4 | |
| Fumaric Acid SCHEMBL8051620 | 0.78 | MEN1 (0.51) | MEN1KMT2ADRD2GRM2DRD4 | |
| SCHEMBL6352566 | 0.70 | MEN1 (0.86) | MEN1KMT2ADRD2GRM2DRD4 | |
| SCHEMBL7933353 | 0.70 | DRD4 (0.50) | MEN1KMT2ADRD2DRD4MAPK1 | |
| SCHEMBL7939813 | 0.69 | HTR1A (0.58) | DRD2DRD4 | |
| SCHEMBL8034282 | 0.68 | MEN1 (0.82) | MEN1KMT2ADRD2GRM2DRD4 | |
| SCHEMBL15965539 | 0.68 | MEN1 (0.61) | MEN1KMT2ADRD2GRM2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053235-A1 | OXAZOLE DERIVATIVES AS SEROTONIN-1A RECEPTOR AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-22 | — | — | EP | claimed |
| US-6057340-A | Oxazole derivatives as serotonin-1A receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-02 | — | — | US | claimed |
| WO-1999038864-A1 | OXAZOLE DERIVATIVES AS SEROTONIN-1A RECEPTOR AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-05 | — | — | WO | claimed |
| US-6057340-A | Oxazole derivatives as serotonin-1A receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |