Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939817 | 0.94 | MAPK1 (0.56) | DRD4HTR7MAPTMAPK1ALDH1A1 | |
| SCHEMBL7940912 | 0.90 | MAPT (0.47) | DRD4HTR7MAPTMAPK1ALDH1A1 | |
| SCHEMBL8049534 | 0.86 | MEN1 (0.58) | DRD4MAPK1MEN1KMT2ADRD2 | |
| SCHEMBL7942668 | 0.85 | SLC6A2 (0.51) | DRD4HTR7MAPTMAPK1ALDH1A1 | |
| SCHEMBL7939791 | 0.82 | MAPT (0.63) | DRD4HTR7MAPTMAPK1ALDH1A1 | |
| SCHEMBL7939807 | 0.82 | HTR1A (0.56) | DRD4HTR7DRD2DRD3HTR1A | |
| SCHEMBL7939857 | 0.82 | ALDH1A1 (0.47) | DRD4HTR7ALDH1A1MEN1KMT2A | |
| SCHEMBL7939196 | 0.81 | DRD4 (0.53) | DRD4HTR7MAPTMAPK1ALDH1A1 | |
| SCHEMBL7939820 | 0.80 | DRD2 (0.57) | DRD4HTR7MAPTMEN1KMT2A | |
| Fumaric Acid SCHEMBL8051620 | 0.80 | MEN1 (0.51) | DRD4MAPK1MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | claimed |
| US-6242448-B1 | Trisubstituted-oxazole derivatives as serotonin ligands | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |