Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25802171 | 1.00 | TSHR (0.43) | TSHRCES2FAAHALDH1A1LMNA | |
| SCHEMBL1036985 | 0.98 | TSHR (0.44) | TSHRCES2FAAHALDH1A1LMNA | |
| SCHEMBL26699205 | 0.92 | TSHR (0.46) | TSHRCES2FAAHALDH1A1LMNA | |
| SCHEMBL831512 | 0.83 | — | — | |
| SCHEMBL7053347 | 0.82 | CES2 (0.64) | CES2FAAH | |
| SCHEMBL29084475 | 0.82 | GAA (0.47) | TSHRCES2ALDH1A1HSD17B10MGAM | |
| SCHEMBL6137569 | 0.81 | ALDH1A1 (0.47) | TSHRCES2FAAHALDH1A1HSD17B10 | |
| SCHEMBL9773565 | 0.81 | ALDH1A1 (0.47) | TSHRCES2FAAHALDH1A1HSD17B10 | |
| SCHEMBL21901982 | 0.81 | ALDH1A1 (0.47) | TSHRCES2FAAHALDH1A1HSD17B10 | |
| SCHEMBL22906936 | 0.81 | ALDH1A1 (0.47) | TSHRCES2FAAHALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245317-B1 | F18-labeled oxa fatty acids and methods of making and using the same | DUKE UNIVERSITY | 2001-06-12 | — | — | US | disclosed |
| WO-2000063416-A2 | F18-LABELED OXA FATTY ACIDS AND METHODS OF MAKING AND USING THE SAME | DUKE UNIVERSITY (US) | 2000-10-26 | — | — | WO | disclosed |