SCHEMBL7939852

SCHEMBL7939852

O=C(c1cc(O)cc(O)c1)c1cc(O)cc(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FASN P49327 2/20 0.70
CA12 O43570 4/20 0.63
CA1 P00915 4/20 0.63
CA2 P00918 4/20 0.63
CA7 P43166 4/20 0.63
CA9 Q16790 4/20 0.63
CA14 Q9ULX7 4/20 0.63
CA5A P35218 1/20 0.60
BACE1 P56817 1/20 0.53
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
NQO2 P16083 1/20 0.44
HCAR1 Q9BXC0 3/20 0.44
SRD5A2 P31213 1/20 0.42
CLK1 P49759 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3545449 0.87 HTT (0.75) FASNCA12CA1CA2CA7
SCHEMBL18529821 0.84 FASN (0.54) FASNCA12CA1CA2CA7
SCHEMBL366721 0.84 ALDH1A1 (0.67) FASNCA12CA1CA2CA7
SCHEMBL8648142 0.84 FASN (0.54) FASNCA12CA1CA2CA7
SCHEMBL9639010 0.83 FASN (1.00) FASNCA12CA1CA2CA7
SCHEMBL8861197 0.83 FASN (0.74) FASNCA12CA1CA2CA9
SCHEMBL5712143 0.81 HTT (0.75) FASNCA12CA1CA2CA7
SCHEMBL22336666 0.81 LTA4H (0.55) FASNCA1CA2ESR1ESR2
SCHEMBL8861226 0.81 SIRT1 (0.56) FASNCA12CA1CA2CA7
SCHEMBL5712141 0.79 ATM (0.70) FASNCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101365744-A Benzoylresorcinol-based phosphate ester compouds as flame retardants INDSPEC CHEMICAL CORP (US) 2009-02-11 CN disclosed
US-6245478-B1 Resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-12 US disclosed
US-5686557-A Polyamide resin which can be dissolved in alcohol solvent, composition thereof, and method of use thereof TOMOEGAWA PAPER CO., LTD. (JP) 1997-11-11 US disclosed