Sugi Predict

Sugi Predict / Compounds / SCHEMBL9639010

SCHEMBL9639010

SCHEMBL9639010

O=C(c1cc(O)cc(O)c1)c1c(O)cc(O)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FASN P49327 2/20 1.00
▸ CYP3A4 P08684 4/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ HPGD P15428 1/20 0.54
▸ CA12 O43570 4/20 0.52
▸ CA1 P00915 4/20 0.52
▸ CA2 P00918 4/20 0.52
▸ CA7 P43166 4/20 0.52
▸ CA9 Q16790 4/20 0.52
▸ CA14 Q9ULX7 4/20 0.52
▸ CA5A P35218 1/20 0.50
▸ PTGS1 P23219 1/20 0.48
▸ DRD3 P35462 1/20 0.48
▸ ACHE P22303 2/20 0.46
▸ NR1H2 P55055 1/20 0.43
▸ NR1H3 Q13133 1/20 0.43
▸ SYNJ2 O15056 1/20 0.43
▸ BACE1 P56817 1/20 0.42
▸ NQO1 P15559 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6272879 0.86 FASN (0.75) FASNCYP3A4MEN1KMT2AHPGD
SCHEMBL352504 0.85 FASN (0.74) FASNCYP3A4MEN1KMT2AHPGD
SCHEMBL3656921 0.84 FASN (0.73) FASNCYP3A4MEN1KMT2AHPGD
SCHEMBL8861225 0.83 FASN (0.71) FASNCYP3A4CA12CA1CA2
SCHEMBL7939852 0.83 FASN (0.70) FASNHPGDCA12CA1CA2
SCHEMBL8651998 0.81 FASN (0.68) FASNCYP3A4MEN1KMT2AHPGD
Iriflophenone SCHEMBL9148205 0.80 FASN (0.67) FASNCYP3A4MEN1KMT2AHPGD
SCHEMBL2315545 0.80 FASN (0.65) FASNMEN1KMT2ACA12CA1
SCHEMBL6847967 0.78 FASN (0.64) FASNCYP3A4MEN1KMT2AHPGD
SCHEMBL353943 0.78 FASN (0.64) FASNCYP3A4MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 — — US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 — — US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 — — US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 — — EP disclosed
US-20190290564-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-09-26 — — US disclosed
US-20190254943-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-08-22 — — US disclosed
US-20190224093-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-07-25 — — US disclosed
US-20190125052-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-05-02 — — US disclosed
EP-3463264-A1 METHOD FOR TREATING HAIR Kao Corporation (JP) 2019-04-10 — — EP disclosed
EP-3463265-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 2019-04-10 — — EP disclosed
US-20180353406-A1 AGENT FOR HAIR DEFORMING TREATMENT KAO CORPORATION (JP) 2018-12-13 — — US disclosed
US-20180311129-A1 AGENT FOR HAIR DEFORMING TREATMENT KAO CORPORATION (JP) 2018-11-01 — — US disclosed
WO-2017207768-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2017-12-07 — — WO disclosed
WO-2017207786-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 — — WO disclosed
EP-3228302-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 — — EP disclosed
EP-3228300-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 — — EP disclosed
CN-106999382-A Hair deformation process agent 花王株式会社 2017-08-01 — — CN disclosed
EP-0227487-B1 POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-07-15 — — EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 — — US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C FASN 2277/4885CYP3A4 1895/4885MEN1 1443/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR FASN 2040/4885CYP3A4 1786/4885MEN1 1687/4885
US-20180353406-A1 AGENT FOR HAIR DEFORMING TREATMENT GRHPR, SLC26A4, COL1A1 FASN 2900/4885CYP3A4 3291/4885MEN1 1850/4885
US-20190254943-A1 HAIR COSMETIC COMPOSITION CUTA, POLR1C, GRHPR FASN 2040/4885CYP3A4 1786/4885MEN1 1687/4885
US-20180311129-A1 AGENT FOR HAIR DEFORMING TREATMENT COL1A1, COL2A1, GRHPR FASN 2319/4885CYP3A4 4297/4885MEN1 1506/4885
US-20190125052-A1 METHOD FOR TREATING HAIR GRHPR, TYR, POLR1C FASN 1844/4885CYP3A4 848/4885MEN1 2426/4885
US-20190224093-A1 HAIR COSMETIC COMPOSITION CUTA, GRHPR, POLR1C FASN 2277/4885CYP3A4 1895/4885MEN1 1443/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 FASN 2900/4885CYP3A4 3291/4885MEN1 1850/4885
US-20190290564-A1 HAIR COSMETIC COMPOSITION GRHPR, POLR1C, TYR FASN 2229/4885CYP3A4 1647/4885MEN1 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.