Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668231 | 0.79 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL18826085 | 0.75 | MAT2A (0.35) | ALDH1A1ALOX15TSHRLMNACYP1A2 | |
| SCHEMBL7930932 | 0.72 | SLC29A1 (0.47) | SLC29A1KMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL6462055 | 0.72 | MEN1 (0.39) | MEN1KMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL6747378 | 0.71 | XDH (0.37) | MEN1KMT2ATMIGD3HTR2CHTR2B | |
| SCHEMBL14553097 | 0.70 | PRKCI (0.40) | MEN1KMT2ABLM | |
| SCHEMBL31299375 | 0.68 | — | — | |
| SCHEMBL25136825 | 0.67 | — | — | |
| SCHEMBL7940047 | 0.66 | HTT (0.36) | SLC29A1MEN1KMT2A | |
| SCHEMBL6465219 | 0.65 | GLP1R (0.34) | MEN1KMT2AALDH1A1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |