SCHEMBL7940127

SCHEMBL7940127

c1ccc(Nc2nc(Nc3ccccc3)c3nc(Nc4ccccc4)nc(Nc4ccccc4)c3n2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 5/20 0.63
MEN1 O00255 2/20 0.55
MAPT P10636 2/20 0.55
KMT2A Q03164 2/20 0.55
GAA P10253 2/20 0.55
NFKB1 P19838 1/20 0.55
MAPK1 P28482 1/20 0.55
KDM4E B2RXH2 1/20 0.55
IGF1R P08069 2/20 0.55
GSK3B P49841 2/20 0.55
JAK2 O60674 2/20 0.55
PLK4 O00444 1/20 0.55
AURKA O14965 1/20 0.55
PDPK1 O15530 1/20 0.55
PRKD3 O94806 1/20 0.55
MAP4K4 O95819 1/20 0.55
NTRK1 P04629 1/20 0.55
INSR P06213 1/20 0.55
LCK P06239 1/20 0.55
FYN P06241 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13320047 0.89 IGF1R (0.54) NPY5RMEN1MAPTKMT2AGAA
SCHEMBL7937469 0.88 EGFR (0.55) NPY5RMEN1MAPTKMT2AGAA
SCHEMBL633400 0.81 MEN1 (0.77) NPY5RMEN1MAPTKMT2AGAA
SCHEMBL13861627 0.81 NPY5R (0.61) NPY5RMEN1MAPTKMT2AGAA
SCHEMBL7930879 0.79 NPY5R (0.58) NPY5RMEN1MAPTKMT2AGAA
SCHEMBL459413 0.79 IGF1R (0.51) NPY5RMEN1MAPTKMT2AGAA
SCHEMBL2591063 0.78 NPY5R (1.00) NPY5RMEN1KMT2ANFKB1MAPK1
SCHEMBL7930912 0.77 MEN1 (0.59) NPY5RMEN1MAPTKMT2ANFKB1
SCHEMBL18123046 0.77 MEN1 (0.71) NPY5RMEN1MAPTKMT2AGAA
Hydrochloric Acid SCHEMBL6039677 0.76 NPY5R (0.96) NPY5RMEN1MAPTKMT2ANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346772-A HAVING A HIGH LUMINANCE AND HIGH EMISSION EFFICIENCY PIONEER ELECTRONIC CORPORATION (JP) 1994-09-13 US claimed
US-7719000-B2 Organic semiconductor materials using stacking-inducing compounds, compositions comprising such materials, organic semiconductor thin films formed using such compositions, and organic electronic devices incorporating such thin films SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-05-18 US disclosed
US-7719000-B2 Organic semiconductor materials using stacking-inducing compounds, compositions comprising such materials, organic semiconductor thin films formed using such compositions, and organic electronic devices incorporating such thin films SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-05-18 US disclosed
US-7632947-B2 Pyrimidopyrimidine derivatives, organic thin film transistors using pyrimidopyrimidine derivatives and method for fabricating the same SAMSUNG ELECTRONICS CO., LTD (KR) 2009-12-15 US disclosed
US-7632947-B2 Pyrimidopyrimidine derivatives, organic thin film transistors using pyrimidopyrimidine derivatives and method for fabricating the same SAMSUNG ELECTRONICS CO., LTD (KR) 2009-12-15 US disclosed
US-20070287220-A1 Organic semiconductor materials using stacking-inducing compounds, compositions comprising such materials, organic semiconductor thin films formed using such compositions, and organic electronic devices incorporating such thin films SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-12-13 US disclosed
US-20070287220-A1 Organic semiconductor materials using stacking-inducing compounds, compositions comprising such materials, organic semiconductor thin films formed using such compositions, and organic electronic devices incorporating such thin films SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-12-13 US disclosed
US-6232312-B1 ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER CELL PATHWAYS, INC. 2001-05-15 US disclosed
US-5346772-A HAVING A HIGH LUMINANCE AND HIGH EMISSION EFFICIENCY PIONEER ELECTRONIC CORPORATION (JP) 1994-09-13 US disclosed
EP-0583861-A1 Organic electroluminescene device PIONEER ELECTRONIC CORPORATION (JP) 1994-02-23 EP disclosed