Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939982 | 0.88 | KDR (0.50) | NPY5RPOLBMEN1KMT2AADORA3 | |
| SCHEMBL11630110 | 0.83 | KCNH3 (0.59) | NPY5RPOLBMEN1KMT2AGAA | |
| SCHEMBL7939006 | 0.82 | MAPT (0.44) | NPY5RMEN1KMT2AGAAADORA3 | |
| SCHEMBL7940127 | 0.79 | NPY5R (0.63) | NPY5RMEN1KMT2AGAAKDR | |
| SCHEMBL9390360 | 0.77 | MAPT (0.69) | POLBMEN1KMT2ANR1I2AHR | |
| SCHEMBL21914641 | 0.77 | TXN (0.58) | NPY5RPOLBMEN1KMT2AGAA | |
| SCHEMBL3500246 | 0.77 | NFKB1 (0.69) | POLBMEN1KMT2AGAAADORA3 | |
| SCHEMBL9351742 | 0.76 | MAPT (0.62) | NPY5RMEN1KMT2AGAAKCNH3 | |
| SCHEMBL8892229 | 0.75 | NPY5R (0.97) | NPY5RPOLBMEN1KMT2AGAA | |
| SCHEMBL16114026 | 0.74 | POLB (0.51) | NPY5RPOLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |