Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467226 | 0.90 | RECQL (0.53) | RECQLKMT2APOLBMEN1PDE4B | |
| SCHEMBL7418284 | 0.79 | RECQL (0.47) | RECQLKMT2AMEN1PDE4BPDE4A | |
| SCHEMBL7376963 | 0.78 | HTT (0.52) | RECQLKMT2APOLBSMN1; SMN2MEN1 | |
| SCHEMBL7471407 | 0.75 | PDE4B (0.50) | RECQLKMT2APOLBMEN1PDE4B | |
| SCHEMBL7412528 | 0.75 | TPH1 (0.47) | RECQLKMT2APOLBMEN1PDE4B | |
| SCHEMBL6571638 | 0.74 | POLB (0.50) | RECQLPOLBPDE4BPDE4APDE4C | |
| SCHEMBL7937749 | 0.73 | TPH1 (0.51) | RECQLKMT2APOLBMEN1PDE4B | |
| SCHEMBL7415564 | 0.73 | TPH1 (0.51) | RECQLKMT2APOLBMEN1PDE4B | |
| SCHEMBL7422273 | 0.72 | RECQL (0.47) | RECQLKMT2AMEN1PDE4BPDE4A | |
| SCHEMBL7420665 | 0.72 | PDE4B (0.48) | RECQLPOLBPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248769-B1 | ANTIINFLAMMATORY AGENT | EURO-CELTIQUE S.A. (LU) | 2001-06-19 | — | — | US | disclosed |