Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940575 | 1.00 | APP (0.44) | APPLMNAMAPTADRA2AADRA2B | |
| SCHEMBL12387901 | 0.83 | MAPT (0.47) | APPLMNAMAPTADRA2AADRA2B | |
| SCHEMBL8533249 | 0.83 | MAPT (0.47) | APPLMNAMAPTADRA2AADRA2B | |
| SCHEMBL9391329 | 0.81 | ALDH1A1 (0.48) | APPLMNAMAPTADRA2AADRA2B | |
| SCHEMBL27619557 | 0.80 | APP (0.44) | APPLMNAMAPTADRA2AADRA2B | |
| SCHEMBL5640005 | 0.79 | ALDH1A1 (0.50) | APPLMNAMAPTADRA2AADRA2B | |
| SCHEMBL27638404 | 0.78 | APP (0.50) | APPLMNAMAPTADRA2AADRA2B | |
| SCHEMBL16614459 | 0.78 | APP (0.72) | APP | |
| SCHEMBL8422585 | 0.76 | LMNA (0.53) | APPLMNAMAPTADRA2AALDH1A1 | |
| SCHEMBL12802293 | 0.74 | THRB (0.46) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242648-B1 | USING THE ULLMANN REACTION; HIGH YIELD, COST REDUCTION | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |