Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.52 |
| ▸ | GPR3 | P46089 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255560 | 0.87 | GPR3 (0.52) | CHRNA7GPR3GAAMAPTEPHX2 | |
| SCHEMBL6241207 | 0.83 | KIF11 (0.46) | CHRNA7GPR3MAPTEPHX2DHFR | |
| SCHEMBL7935587 | 0.82 | CHRNA7 (0.42) | CHRNA7GPR3GAAMAPTRHEB | |
| SCHEMBL12953084 | 0.82 | CYP3A4 (0.56) | CHRNA7GPR3MAPTEPHX2DHFR | |
| SCHEMBL15207305 | 0.82 | CHRNA7 (0.53) | CHRNA7GPR3MAPTEPHX2DHFR | |
| SCHEMBL7938064 | 0.82 | NR1H2 (0.56) | CHRNA7GPR3MAPTEPHX2DHFR | |
| SCHEMBL7938385 | 0.80 | KIF11 (0.50) | GPR3GAAMAPTEPHX2HSD11B1 | |
| SCHEMBL7937983 | 0.80 | GPR3 (0.47) | CHRNA7GPR3GAAMAPTEPHX2 | |
| SCHEMBL944451 | 0.78 | EPHX2 (0.50) | CHRNA7GPR3MAPTEPHX2DHFR | |
| SCHEMBL24512622 | 0.77 | PIM1 (0.43) | CHRNA7GPR3MAPTEPHX2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |