SCHEMBL944451

SCHEMBL944451

FC(F)(F)Oc1ccc(SSc2ccc(OC(F)(F)F)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.50
MAPT P10636 3/20 0.45
GPR3 P46089 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
KIF11 P52732 2/20 0.40
NOS3 P29474 2/20 0.40
NOS1 P29475 2/20 0.40
NOS2 P35228 2/20 0.40
PDE2A O00408 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
FAAH O00519 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
CHRNA7 P36544 2/20 0.38
MAOB P27338 1/20 0.38
AOC3 Q16853 1/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254957 0.84 MAPT (0.56) EPHX2MAPTGPR3L3MBTL1KDM4E
SCHEMBL5043580 0.81 MAPT (0.42) EPHX2MAPTGPR3L3MBTL1KDM4E
SCHEMBL17791002 0.81 MAPT (0.47) EPHX2MAPTGPR3L3MBTL1KDM4E
SCHEMBL514679 0.81 MAPT (0.42) EPHX2MAPTGPR3L3MBTL1KDM4E
SCHEMBL514680 0.81 CYP1A1 (0.44) EPHX2MAPTGPR3L3MBTL1KDM4E
SCHEMBL4116218 0.81 MAPT (0.42) EPHX2MAPTGPR3L3MBTL1KDM4E
SCHEMBL2949216 0.81 MAPT (0.42) EPHX2MAPTGPR3L3MBTL1KDM4E
SCHEMBL13923555 0.78 PDE2A (0.42) EPHX2MAPTGPR3L3MBTL1KIF11
SCHEMBL7940692 0.78 CHRNA7 (0.52) EPHX2MAPTGPR3L3MBTL1ALDH1A1
SCHEMBL7955721 0.78 MAPT (0.40) EPHX2MAPTGPR3L3MBTL1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390626-A NHC-BH3Method for synthesizing disulfide derivative based on sulfonyl hydrazine under catalysis 湖南大学 2025-02-07 CN disclosed
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 EP disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 EP disclosed
EP-2468719-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-10-16 EP disclosed
EP-2137144-B1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES UBE INDUSTRIES (JP) 2013-07-31 EP disclosed
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 US disclosed
EP-2468719-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
EP-2468721-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US disclosed
EP-2137144-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T Research, Inc. (US) 2009-12-30 EP disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 US disclosed
EP-1768667-B1 CANNABINOID RECEPTOR LIGANDS SCHERING CORP (US) 2009-09-30 EP disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 US disclosed
WO-2008118787-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM & T RESEARCH, INC. (US) 2008-10-02 WO disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 US disclosed
EP-1768667-A1 CANNABINOID RECEPTOR LIGANDS SCHERING CORPORATION (US) 2007-04-04 EP disclosed
US-20060100228-A1 Cannabinoid receptor ligands SCHERING CORPORATION 2006-05-11 US disclosed
WO-2006002133-A1 CANNABINOID RECEPTOR LIGANDS SCHERING CORPORATION (US) 2006-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100228-A1 Cannabinoid receptor ligands CNR1, CNR2, TRPV1 EPHX2 1571/4885MAPT 2622/4885GPR3 8/4885
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA EPHX2 1946/4885MAPT 3764/4885GPR3 3475/4885
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES PFAS, MPST, ARSA EPHX2 1946/4885MAPT 3764/4885GPR3 3475/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA EPHX2 1946/4885MAPT 3764/4885GPR3 3475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.