Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876840 | 0.79 | F2 (0.51) | KDM4ENPC1L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL26706918 | 0.79 | NOS2 (0.57) | KDM4ENPC1L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL27893661 | 0.79 | GRIN2D (0.49) | KDM4ENPC1L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL10920047 | 0.79 | F2 (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6761973 | 0.79 | KDM4E (0.57) | KDM4ENPC1L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL7013357 | 0.76 | NOS2 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14875866 | 0.75 | HDAC6 (0.54) | — | |
| SCHEMBL18135105 | 0.74 | KDR (0.48) | KDM4ENOS2HTTASPHKDM8 | |
| SCHEMBL18608757 | 0.74 | CDC7 (0.52) | KDM4ENPC1L3MBTL1NOS2FABP1 | |
| SCHEMBL2126955 | 0.74 | F2 (0.70) | F2FABP1FABP6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3018125-B1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | SHIN NIPPON BIOMEDICAL LABORATORIES LTD (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
| EP-3018125-A1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | Shin Nippon Biomedical Laboratories, Ltd. (JP) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015002150-A1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | 株式会社新日本科学 (JP) | 2015-01-08 | — | — | WO | disclosed |
| US-8569336-B2 | Compounds for the treatment of inflammatory disorders | TONG LING (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569336-B2 | Compounds for the treatment of inflammatory disorders | TONG LING (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TONG LING (US) | 2012-01-19 | — | — | US | disclosed |
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TONG LING (US) | 2012-01-19 | — | — | US | disclosed |
| WO-2010054278-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SLCO1B3, SLC22A8, SLC10A6 | KDM4E 4373/4885NPC1 135/4885L3MBTL1 2428/4885 |
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TNF, ADAMTS1, ADAMTS7 | KDM4E 4592/4885NPC1 519/4885L3MBTL1 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.