SCHEMBL7940884

SCHEMBL7940884

CC(C)(C)[Si](C)(C)OC1=Cc2ccccc2[CH]1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA9 Q16790 4/20 0.32
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
PREP P48147 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8210276 0.80
SCHEMBL217368 0.79
SCHEMBL7635858 0.70 LMNA (0.33) CA12CA1CA9
SCHEMBL30556213 0.70 CA1 (0.38) CA12CA1CA9ALOX5APFEN1
SCHEMBL4438037 0.69 ALDH1A1 (0.44) CA12CA1CA9ALOX5APFEN1
SCHEMBL2368966 0.69 PREP (0.45) CA12CA1CA9PREP
SCHEMBL3687729 0.68
SCHEMBL6907784 0.68 PTGS2 (0.37) PREP
SCHEMBL218179 0.68
SCHEMBL756303 0.68 CA1 (0.39) CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001070395-A2 POLYMERIZATION CATALYSTS COMPRISING AN OPEN ETA-5 LIGAND BOREALIS TECHNOLOGY OY (FI) 2001-09-27 WO claimed
CN-102217006-B Cable and polymer composition including multimodal ethylene copolymer BOREALIS AG (AT) 2016-11-30 CN disclosed
CN-102217006-A Cable and polymer composition comprising a multimodal ethylene copolymer BOREALIS AG 2011-10-12 CN disclosed
WO-2001070395-A2 POLYMERIZATION CATALYSTS COMPRISING AN OPEN ETA-5 LIGAND BOREALIS TECHNOLOGY OY (FI) 2001-09-27 WO disclosed
EP-0975644-A1 SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS, THEIR INTERMEDIATES AND METHODS FOR PREPARING THEM BOREALIS A/S (DK) 2000-02-02 EP disclosed
WO-1998046616-A1 SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS, THEIR INTERMEDIATES AND METHODS FOR PREPARING THEM BOREALIS A/S (DK) 1998-10-22 WO disclosed