Acetic Acid

Acetic Acid

SCHEMBL7941016

CC(=O)O.CCOC(O)CC

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 4/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36
FFAR3 O14843 2/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62770 0.87
Water SCHEMBL27524942 0.84
Acetic Acid SCHEMBL11202022 0.83 LMNA (0.35) TSHRALDH1A1LMNAHSD17B10FFAR3
Methylamine SCHEMBL770281 0.81
Acetic Acid SCHEMBL8816064 0.81 CHRM1 (0.41) TSHRALDH1A1LMNAHSD17B10FFAR3
Acetic Acid SCHEMBL25399091 0.79 RNPEP (0.37) ALDH1A1LMNAHSD17B10TDP1
Acetic Acid SCHEMBL297194 0.77 LMNA (0.41) TSHRALDH1A1LMNAHSD17B10FFAR3
Acetic Acid SCHEMBL29076 0.77 TSHR (0.46) TSHRALDH1A1LMNAHSD17B10FFAR3
Acetic Acid Propyl Ester SCHEMBL18204393 0.76 ALDH1A1 (0.44) TSHRALDH1A1LMNAHSD17B10
Acetic Acid SCHEMBL8454146 0.76 THRB (0.65) TSHRALDH1A1LMNAHSD17B10FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113574127-B Composite aqueous inkjet fluid 太阳化学公司 2022-09-27 CN disclosed
CN-113574127-A Composite aqueous inkjet fluid 太阳化学公司 2021-10-29 CN disclosed
CN-113045029-A Treatment method of paint spraying wastewater 东江环保股份有限公司 2021-06-29 CN disclosed
US-9105796-B2 CZTS/Se precursor inks and methods for preparing CZTS/Se thin films and CZTS/Se-based photovoltaic cells E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-11 US disclosed
US-20150118144-A1 DISPERSIBLE METAL CHALCOGENIDE NANOPARTICLES E I DU PONT NEMOURS AND COMPANY (US) 2015-04-30 US disclosed
WO-2013172949-A1 DISPERSIBLE METAL CHALCOGENIDE NANOPARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-11-21 WO disclosed
US-20130125988-A1 CZTS/Se PRECURSOR INKS AND METHODS FOR PREPARING CZTS/Se THIN FILMS AND CZTS/Se-BASED PHOTOVOLTAIC CELLS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-05-23 US disclosed
US-6323362-B1 TRANSESTERIFICATION OF ACETATE COMPOUND WITH ALCOHOL IN PRESENCE OF CATALYST BP CHEMICALS LIMITED (GB) 2001-11-27 US disclosed
EP-0849254-B1 A continuous process for producing esters BP CHEM INT LTD (GB) 2001-08-29 EP disclosed
EP-0849254-A1 A continuous process for producing esters BP Chemicals Limited (GB) 1998-06-24 EP disclosed