Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14883384 | 0.88 | CA2 (0.48) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL8409756 | 0.86 | ALDH1A1 (0.55) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL7941133 | 0.83 | CA2 (0.47) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL7944832 | 0.82 | ALDH1A1 (0.48) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL8055820 | 0.80 | HSD17B10 (0.53) | CA2GABRA1GABRB2ALDH1A1HPGD | |
| SCHEMBL8407642 | 0.80 | CA2 (0.47) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL8411002 | 0.79 | CA2 (0.46) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL14853268 | 0.78 | CA2 (0.48) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL7942593 | 0.77 | HIF1A (0.55) | ALDH1A1KDM4EMAPTHPGDMAPK1 | |
| SCHEMBL7943247 | 0.77 | HSPA5 (0.58) | CA2ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |