SCHEMBL8055820

SCHEMBL8055820

CN(CCO)Cc1cccc(O)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.53
IAPP P10997 4/20 0.42
DRD1 P21728 1/20 0.41
DRD3 P35462 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
HTR2A P28223 2/20 0.41
ADAMTS4 O75173 1/20 0.38
ALDH1A1 P00352 1/20 0.38
EGFR P00533 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38
FYN P06241 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
MMP8 P22894 1/20 0.38
CA6 P23280 1/20 0.38
CDK2 P24941 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31404238 0.85 HSD17B10 (0.56) HSD17B10DRD1DRD3SIGMAR1HTR2A
SCHEMBL8815147 0.85 HSD17B10 (0.56) HSD17B10DRD1DRD3SIGMAR1HTR2A
SCHEMBL7941366 0.80 CA2 (0.48) HSD17B10SIGMAR1HTR2AALDH1A1CA2
SCHEMBL9068633 0.79 ALDH1A1 (0.52) HSD17B10IAPPHTR2AADAMTS4ALDH1A1
SCHEMBL17264227 0.78 CYP1A2 (0.44) HSD17B10DRD1DRD3SIGMAR1HTR2A
SCHEMBL16153682 0.76 IAPP (0.47) HSD17B10IAPPALDH1A1HPGDALOX15
SCHEMBL14424853 0.76 CYP2D6 (0.50) HTR2AALDH1A1CA2CYP1A2CYP2D6
SCHEMBL20885393 0.75 MAPT (0.58) HSD17B10DRD1DRD3SIGMAR1ALDH1A1
SCHEMBL15483812 0.75 HSPA5 (0.50) HSD17B10DRD1DRD3SIGMAR1HTR2A
SCHEMBL12432722 0.75 BCHE (0.43) HTR2AALDH1A1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108178730-B Catechol derivative and its bionic polymer synthesis and application 华中师范大学 2021-06-15 CN claimed
CN-108178730-B Catechol derivative and its bionic polymer synthesis and application 华中师范大学 2021-06-15 CN disclosed
EP-0998448-A1 NOVEL N-ALKYL-HYDROXYBENZYLAMINES, PREPARATION METHOD, USES AND COMPOSITIONS CONTAINING THEM CFPI INDUSTRIES (FR) 2000-05-10 EP disclosed
WO-1999005089-A1 NOVEL N-ALKYL-HYDROXYBENZYLAMINES, PREPARATION METHOD, USES AND COMPOSITIONS CONTAINING THEM CFPI INDUSTRIES (FR) 1999-02-04 WO disclosed