Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944832 | 0.92 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL8407642 | 0.91 | CA2 (0.47) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL8411002 | 0.89 | CA2 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL7941366 | 0.86 | CA2 (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL7941133 | 0.84 | CA2 (0.47) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL14853268 | 0.83 | CA2 (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL3809080 | 0.78 | CA2 (0.59) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL10706992 | 0.77 | CA2 (0.64) | ALDH1A1SMN1; SMN2MAPK1CA2GABRA1 | |
| SCHEMBL8407909 | 0.76 | HTT (0.62) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL8411161 | 0.76 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874494-A | DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |