Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.48 |
| ▸ | GLRB | P48167 | 1/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432052 | 0.85 | GLRA3 (0.48) | GLRA3GLRBGABBR2GABBR1CA2 | |
| SCHEMBL10774229 | 0.85 | GLRA3 (0.48) | GLRA3GLRBGABBR2GABBR1CA2 | |
| SCHEMBL11776262 | 0.82 | GLRA3 (0.46) | GLRA3GLRBGABBR2GABBR1CA2 | |
| SCHEMBL9219443 | 0.82 | ALDH1A1 (0.46) | GLRA3GLRBGABBR2GABBR1CA2 | |
| SCHEMBL9774879 | 0.81 | ESR1 (0.45) | GLRA3GLRBCA2CA1ALDH1A1 | |
| SCHEMBL22118122 | 0.81 | LMNA (0.45) | GLRA3GLRBGABBR2GABBR1CA2 | |
| Ethylene Glycol SCHEMBL11704704 | 0.81 | GLRA3 (0.44) | GLRA3GLRBGABBR2GABBR1CA2 | |
| 1,4-Butanediol SCHEMBL11708084 | 0.78 | VCAM1 (0.44) | GLRA3GLRBGABBR2GABBR1CA2 | |
| 1,3-Propanediol SCHEMBL11703970 | 0.78 | GLRA3 (0.42) | GLRA3GLRBGABBR2GABBR1CA2 | |
| 1,6-Hexanediol SCHEMBL11706482 | 0.77 | VCAM1 (0.43) | GLRA3GLRBGABBR2GABBR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |