Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941371 | 0.82 | GLRA3 (0.48) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL11776262 | 0.76 | GLRA3 (0.46) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL8348961 | 0.76 | CA2 (0.52) | ALDH1A1GAACA2CA1SMN1; SMN2 | |
| SCHEMBL11793577 | 0.74 | CA2 (0.54) | ALDH1A1GAACA2CA1SMN1; SMN2 | |
| SCHEMBL30892095 | 0.72 | LMNA (0.46) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL19917541 | 0.72 | GLRA3 (0.42) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL3232508 | 0.72 | CA2 (0.52) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL10774229 | 0.71 | GLRA3 (0.48) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL28432052 | 0.71 | GLRA3 (0.48) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL6918240 | 0.71 | GPR55 (0.37) | ALDH1A1GAATDP1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | claimed |