Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783519 | 0.89 | HTR1A (0.35) | HTR1ADRD2PRCPALDH1A1LMNA | |
| SCHEMBL7986246 | 0.82 | PRCP (0.44) | HTR1ADRD2PRCPALDH1A1LMNA | |
| SCHEMBL28236427 | 0.80 | PRCP (0.43) | HTR1ADRD2PRCP | |
| SCHEMBL31247515 | 0.78 | HTR1A (0.48) | HTR1ADRD2PRCP | |
| SCHEMBL5580304 | 0.77 | HTR1A (0.44) | HTR1ADRD2PRCP | |
| SCHEMBL8520734 | 0.70 | PRCP (0.36) | HTR1ADRD2PRCPALDH1A1LMNA | |
| SCHEMBL24033332 | 0.69 | NPY1R (0.46) | DRD2HTTDRD3 | |
| SCHEMBL3801626 | 0.68 | PRCP (0.36) | HTR1APRCP | |
| SCHEMBL3264741 | 0.68 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL2844780 | 0.68 | PRCP (0.36) | HTR1ADRD2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242438-B1 | 3-Azetidinylalkylpiperidines or -pyrrolidines as tachykinin antagonists | PFIZER INC. | 2001-06-05 | — | — | US | disclosed |