Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 15/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31247515 | 0.92 | HTR1A (0.48) | PRCPHTR1ADRD2 | |
| SCHEMBL5580304 | 0.87 | HTR1A (0.44) | PRCPHTR1ADRD2 | |
| SCHEMBL7941591 | 0.82 | HTR1A (0.38) | PRCPHTR1ADRD2ALDH1A1LMNA | |
| SCHEMBL9824237 | 0.81 | HTR1A (0.40) | PRCPHTR1ADRD2 | |
| SCHEMBL7283540 | 0.80 | HTR1A (0.40) | PRCPHTR1ADRD2 | |
| SCHEMBL7283546 | 0.80 | HTR1A (0.40) | PRCPHTR1ADRD2 | |
| SCHEMBL3264150 | 0.80 | CHRM2 (0.34) | DRD2ALDH1A1CHRM2 | |
| SCHEMBL10839988 | 0.79 | SLC18A3 (0.36) | PRCPHTR1ADRD2 | |
| SCHEMBL9824261 | 0.79 | SLC18A3 (0.36) | PRCPHTR1ADRD2 | |
| SCHEMBL4783519 | 0.78 | HTR1A (0.35) | PRCPHTR1ADRD2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194113-A2 | Process for preparing cis N-alkylperhydroquinolines | ELI LILLY AND COMPANY (US) | 1986-09-10 | — | — | EP | claimed |
| US-4595754-A | Process for preparing cis N-alkylperhydroquinolines | ELI LILLY AND COMPANY (US) | 1986-06-17 | — | — | US | claimed |
| JP-62129272-A | — | — | None | — | — | JP | disclosed |
| JP-62123161-A | — | — | None | — | — | JP | disclosed |
| US-6271264-B1 | REMOVING BILE ACIDS FROM PATIENTS | GELTEX PHARMACEUTICALS, INC. | 2001-08-07 | — | — | US | disclosed |
| WO-2000032656-A2 | POLYMERS CONTAINING SPIROBICYCLIC AMMONIUM MOIETIES AND USE THEREOF | GELTEX PHARMACEUTICALS, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| EP-0194113-A3 | PROCESS FOR PREPARING CIS N-ALKYLPERHYDROQUINOLINES | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| JP-S62129272-A | METHOD FOR PURIFYING PERFLUORO COMPOUND | NIPPON STEEL CHEM CO LTD | 1987-06-11 | — | — | JP | disclosed |
| JP-S62123161-A | NOVEL N,N,N',N'-TETRACYCLOHEXYL-DICARBOXYLIC ACID DIAMIDE | MITSUBISHI CORP | 1987-06-04 | — | — | JP | disclosed |
| US-4647667-A | Octa- and deca-hydroquinoline intermediates | ELI LILLY AND COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0194113-A2 | Process for preparing cis N-alkylperhydroquinolines | ELI LILLY AND COMPANY (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4595754-A | Process for preparing cis N-alkylperhydroquinolines | ELI LILLY AND COMPANY (US) | 1986-06-17 | — | — | US | disclosed |
| US-4595754-A | Process for preparing cis N-alkylperhydroquinolines | ELI LILLY AND COMPANY (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0171277-A2 | Improvements in or relating to tricycling quinoline derivatives | ELI LILLY AND COMPANY (US) | 1986-02-12 | — | — | EP | disclosed |
| US-4567266-A | Method of preparing octahydro-1H(and 2H)-pyrazolo[3,4-g]quinolines | ELI LILLY AND COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| US-4565871-A | INTERMEDIATES FOR ULTRAVIOLET ABSORBERS USED IN SUNSCREENS | ELI LILLY AND COMPANY (US) | 1986-01-21 | — | — | US | disclosed |
| US-4537964-A | Method of preparing permissibly-substituted 1H(and 2H)pyrazolo[3,4-g]quinolines; pyrimido[4,5,g]quinolines; thiazolo[4,5,g]quinolines and intermediates therefore | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0138417-A2 | 2-substituted pyrimidohexahydroquinolines | ELI LILLY AND COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| US-4507478-A | SUNSCREEN AGENTS | ELI LILLY AND COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
| US-3992456-A | BY REACTING BUTADIENE WITH WATER IN THE PRESENCE OF A PALLADIUM CATALYST | UNION CARBIDE CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |