Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682834 | 0.82 | LTA4H (0.60) | LTA4HCNR2LMNAMEN1KMT2A | |
| SCHEMBL10610559 | 0.78 | LTA4H (0.42) | LTA4HCNR2LMNAMEN1KMT2A | |
| Phenetole SCHEMBL28382133 | 0.74 | LTA4H (0.57) | LTA4HCNR2LMNAMEN1KMT2A | |
| SCHEMBL7941710 | 0.74 | LTA4H (0.40) | LTA4HCNR2LMNAMEN1KMT2A | |
| SCHEMBL7941700 | 0.71 | CNR2 (0.42) | LTA4HCNR2LMNAMEN1KMT2A | |
| SCHEMBL11603275 | 0.71 | MEN1 (0.57) | LTA4HCNR2LMNAMEN1KMT2A | |
| SCHEMBL11420513 | 0.71 | LTA4H (0.57) | LTA4HCNR2LMNAMEN1KMT2A | |
| SCHEMBL824979 | 0.70 | NQO1 (0.70) | LTA4HCNR2MEN1KMT2ARELA | |
| Phenetole SCHEMBL28364557 | 0.70 | LTA4H (0.77) | LTA4HLMNARELAL3MBTL1ALDH1A1 | |
| SCHEMBL686456 | 0.69 | LTA4H (0.59) | LTA4HCNR2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218416-B1 | 1-METHYL-2-NITRO-3-((3-TETRAHYDROFURYL)METHYL)GUANIDINE AND (2,5-DIOXO-3-(2-PROPYNYL)-1-IMIDAZOLIDINYL)METHYL CHRYSANTHEMATE AS ACTIVE SYNERGISTIC COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-17 | — | — | US | disclosed |