Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203937 | 0.92 | NQO1 (0.67) | LTA4HNQO1RELATSHRTDP1 | |
| SCHEMBL27778756 | 0.87 | LTA4H (0.44) | LTA4HNQO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7369820 | 0.86 | LTA4H (0.61) | LTA4HNQO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL682834 | 0.85 | LTA4H (0.60) | LTA4HNQO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11398112 | 0.85 | LTA4H (0.61) | LTA4H | |
| SCHEMBL12230351 | 0.84 | NQO1 (0.56) | LTA4HNQO1MEN1KMT2AGAA | |
| Benzene SCHEMBL28529548 | 0.83 | NQO1 (0.61) | LTA4HNQO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12251553 | 0.83 | ALDH1A1 (0.51) | LTA4HMEN1KMT2AL3MBTL1RELA | |
| SCHEMBL11420513 | 0.82 | LTA4H (0.57) | LTA4HNQO1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29261854 | 0.82 | PSMB1 (0.42) | LTA4HMEN1KMT2AL3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | LTA4H 688/4885NQO1 1563/4885MEN1 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.