Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610555 | 0.79 | CNR2 (0.40) | CNR2L3MBTL1LMNALTA4HMEN1 | |
| SCHEMBL682834 | 0.77 | LTA4H (0.60) | CNR2L3MBTL1LMNALTA4HMEN1 | |
| SCHEMBL7941710 | 0.77 | LTA4H (0.40) | CNR2L3MBTL1LMNALTA4HMEN1 | |
| SCHEMBL7941706 | 0.71 | LTA4H (0.45) | CNR2L3MBTL1LMNALTA4HMEN1 | |
| SCHEMBL19543237 | 0.70 | CNR2 (0.51) | CNR2L3MBTL1LMNALTA4HMEN1 | |
| SCHEMBL11293541 | 0.70 | LMNA (0.67) | L3MBTL1LMNALTA4HALOX5BCHE | |
| SCHEMBL11078857 | 0.69 | MEN1 (0.50) | L3MBTL1LMNAMEN1KMT2ABCHE | |
| SCHEMBL824953 | 0.69 | LMNA (0.64) | L3MBTL1LMNAALOX5BCHE | |
| SCHEMBL824979 | 0.68 | NQO1 (0.70) | CNR2L3MBTL1LTA4HMEN1KMT2A | |
| SCHEMBL686456 | 0.67 | LTA4H (0.59) | CNR2L3MBTL1LMNALTA4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218416-B1 | 1-METHYL-2-NITRO-3-((3-TETRAHYDROFURYL)METHYL)GUANIDINE AND (2,5-DIOXO-3-(2-PROPYNYL)-1-IMIDAZOLIDINYL)METHYL CHRYSANTHEMATE AS ACTIVE SYNERGISTIC COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-17 | — | — | US | disclosed |