Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682834 | 0.80 | LTA4H (0.60) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL7941700 | 0.77 | CNR2 (0.42) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL7941706 | 0.74 | LTA4H (0.45) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL686456 | 0.70 | LTA4H (0.59) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL7369820 | 0.69 | LTA4H (0.61) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL824979 | 0.68 | NQO1 (0.70) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| Benzene SCHEMBL28529548 | 0.67 | NQO1 (0.61) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL11420513 | 0.66 | LTA4H (0.57) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL14622133 | 0.66 | LTA4H (0.57) | LTA4HMEN1KMT2AL3MBTL1CNR2 | |
| SCHEMBL11603275 | 0.66 | MEN1 (0.57) | LTA4HMEN1KMT2AL3MBTL1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218416-B1 | 1-METHYL-2-NITRO-3-((3-TETRAHYDROFURYL)METHYL)GUANIDINE AND (2,5-DIOXO-3-(2-PROPYNYL)-1-IMIDAZOLIDINYL)METHYL CHRYSANTHEMATE AS ACTIVE SYNERGISTIC COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-17 | — | — | US | disclosed |