Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619787 | 0.83 | SMN1; SMN2 (0.46) | ATMMEN1KMT2AHTTHTR2A | |
| SCHEMBL7809644 | 0.79 | SMN1; SMN2 (0.47) | KDM4EMEN1KMT2AHTR2AHTR2C | |
| SCHEMBL7650973 | 0.77 | ATM (0.44) | ATMTDP1KDM4EHPGDHSD17B10 | |
| SCHEMBL1673995 | 0.77 | TDP1 (0.47) | ATMTDP1KDM4EHPGDHSD17B10 | |
| SCHEMBL19181694 | 0.76 | KDM4E (0.44) | ATMTDP1KDM4EHPGDHSD17B10 | |
| SCHEMBL10816083 | 0.75 | HTR1B (0.42) | KDM4EMEN1KMT2AKCNH2ALDH1A1 | |
| SCHEMBL247941 | 0.74 | ATM (0.48) | ATMTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL10740520 | 0.73 | MEN1 (0.46) | ATMMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL246639 | 0.73 | SMN1; SMN2 (0.52) | MEN1KMT2AKCNH2SMN1; SMN2SIGMAR1 | |
| SCHEMBL10816937 | 0.73 | ALDH1A1 (0.47) | TDP1KDM4EMEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197918-B1 | INTERCHANGE REACTION OF DIALKYL CARBONATE AND AROMATIC ALCOHOL; CATALYSIS WITH TITANIUM HALIDE, ALKOXIDE, ARYLOXIDE, OR ACETOXIDE | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0780361-B1 | Manufacturing method for aromatic carbonates | GEN ELECTRIC (US) | 2000-09-06 | — | — | EP | disclosed |
| EP-0779312-B1 | Manufacturing method for polycarbonate | GEN ELECTRIC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5760156-A | Manufacturing method for polycarbonate | GENERAL ELECTRIC COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0780361-A1 | Manufacturing method for aromatic carbonates | GENERAL ELECTRIC COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0779312-A2 | Manufacturing method for polycarbonate | GENERAL ELECTRIC COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |