Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344517 | 0.82 | ABL1 (0.50) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL16581454 | 0.82 | ABL1 (0.52) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL27894657 | 0.77 | SENP1 (0.47) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL30046939 | 0.76 | TRPA1 (0.48) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL1513532 | 0.76 | TRPA1 (0.48) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL7946605 | 0.75 | SENP1 (0.37) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL27989294 | 0.75 | ESR1 (0.46) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL6839847 | 0.75 | ALDH1A1 (0.50) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL26136549 | 0.75 | ABL1 (0.50) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL187251 | 0.74 | GABRA1 (0.46) | ESR1ESR2SENP1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001038438-A2 | FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE CONSISTING OF THE SAME | GENERAL ELECTRIC COMPANY (US) | 2001-05-31 | — | — | WO | disclosed |