SCHEMBL7943071

SCHEMBL7943071

CCCC(CO)c1ncc2nc[nH]c2n1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2640868 0.78
SCHEMBL7943075 0.77 KDM4E (0.41) KDM4ESMN1; SMN2
SCHEMBL1306697 0.76
SCHEMBL6950633 0.74 CDK1 (0.30)
SCHEMBL3578261 0.73 KDM4E (0.32) KDM4E
SCHEMBL14993000 0.70 KDM4E (0.32) KDM4E
SCHEMBL22630554 0.70 KCNH3 (0.38) KDM4E
SCHEMBL20257916 0.70 KCNH3 (0.38) KDM4E
2-Aminopurine SCHEMBL4342851 0.69 ALDH1A1 (0.41) KDM4E
SCHEMBL2640834 0.69 APLNR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1131323-A1 SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES Medivir Aktiebolag (SE) 2001-09-12 EP disclosed
WO-2000008025-A1 SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 2000-02-17 WO disclosed